Dxm plateus - Discord: https://discord.gg/nRKcDcDRmQTwitter: https://twitter.com/MorbidOW2People are always going to ask me how much DXM they should take, and since that’s...

 
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According to Healthline, the amount of dextromethorphan ingested causes different stages of intoxication (known as DXM plateaus): First plateau (100 to 200 milligrams): Users feel mild effects and an uplift in mood, becoming more talkative and energetic. Some say the effects are similar to using ecstasy.Um auf das Sigma Plateau zu kommen reicht es nicht noch höhere Dosen DXM zu konsumieren. Dieser Versuch bringt einen schlimmstenfalls nur in die Klinik und kann auch einen Horror Trip nach sich ziehen wenn man in Panik gerät. Doch bevor ich dazu kommen werde dir zu sagen wie du in das Sigma Level kommst beantworte ich erst mal noch einige Fragen.Dxm is basically if ketamine and mdma had a child. But that is so fucking wrong and kinda right. Dxm is weaker ketamine. Not as many visuals. Still quite diasociation. It does release serotonin like mdma and at a firat plat dose it can be similar to 4mmc. Which is similar to mdma. But way less intense.That dose of nutmeg is not very high at all. A high end dose is considered to be 30g of freshly ground nutmeg, which is like like 5-8 whole kernels depending on the size of the kernel. And it is hard to tell, but the visuals that you experienced don't seem untypical for a high dose of DXM. As for a heart rate of 116, that is not dangerously high.DXM may produce euphoria and mind-altering effects when taken in quantities greater than the recommended treatment dose. People who misuse DXM describe different “plateaus” ranging from mild distortions of color and sound to visual hallucinations and “out-of-body” sensations, and loss of motor control.Emergency contraceptives are measures taken to prevent pregnancy occurring after intercourse has taken place. These include emergency contraceptive pills. Try our Symptom Checker G... NSFW. 1st time and thinking about going straight to the 3rd plateau. Newbie. I never intended on using this as a social drug, so when I did some research it said that all of the social aspects of DXM go down the hatch on the third plateau that's when I decided that I was going straight there. I am going to use 40 Delsym fast release pills 15mg ... DXM may produce euphoria and mind-altering effects when taken in quantities greater than the recommended treatment dose. People who misuse DXM describe different “plateaus” ranging from mild distortions of color and sound to visual hallucinations and “out-of-body” sensations, and loss of motor control.Apr 30, 2024 · Plateau 2: The second plateau of DXM misuse occurs when a person takes a dosage between 200 mg and 400 mg. Feelings of stimulation, euphoria, and hallucinations (mostly visual hallucinations) are associated with these dosages. Plateau 3: At this plateau, individuals will take 300-600 mg of DXM. The effects include euphoria, hallucinations ... Dextromethorphan hydrobromide (DXM HBr) is a semi-synthetic opioid sharing N -methyl- d -aspartate receptor antagonistic properties with its primary …FriedChode. • 5 yr. ago. I mean, everyone is different, but keep in mind poli takes like 3 hours to come up on an empty stomach. I’ve only ever done 534mg of poli, and tbh it was really low. Felt like 120mg dxm hbr. For me it’s about 1/5 as strong as hbr. Start out with one 5oz bottle (888mg of poli) and wait 6 hours.antihistamines. The use of high doses of DXM in combination with alcohol or other drugs is particularly dangerous and deaths have been reported. Abusers of DXM describe the following four dose -dependent “plateaus:” Plateau Dose (mg) Behavioral Effects . 1st 100–200 Mild stimulation 2nd 200–400 Euphoria and hallucinationsCHEMICAL NAME. DXM is a widely available over-the-counter cough suppressant. When taken far above its standard medical dosage, it is a strong dissociative used primarily by teens. Many DXM-containing products (such as Coricidin Cough and Cold) also contain other active ingredients which can be dangerous or fatal in high doses.600 - 1500 mg. Risk of Death. 2,500 - 20,000 mg 1. Duration : 4 - 8 hours (DXM HBR) Duration (extended release) : 6 - 12 hours (DXM Polistirex) Some users report that DXM dosages are affected significantly by bodyweight and lighter users should start with lower dosages. Because everyone reacts differently, it is a better idea to start at …Plateaus. Side effects. Onset. Duration. Stopping a robotrip. Risks. Interactions. Addiction. Harm reduction. Overdose signs. Takeaway. DXM, short for dextromethorphan, is an over-the-counter...plateaus. DXM, probably more than most drugs, tends to exert. its (recreational) effects in separate stages or plateaus, rather than. being linearly dose-dependent. Within a given … Plateaus. DXM has notably different effects at different dosage levels. There are 4 distinctive levels, and we call these levels “plateaus”. Abusers of DXM describe the following three dose-dependent “plateaus”: What is its effect on the body? DXM intoxication involves: • Over-excitability, lethargy, loss of coordination, slurred speech, sweating, hypertension, nausea, vomiting, and involuntary spasmodic movement of the eyeballs The use of high doses of DXM in combination withReddit's advertising model is effectively protecting violent subreddits like r/The_Donald—and making everyday Redditors subsidize it. Reddit has a problem. The website has always p...Jan 31, 2002. Messages. 1,433. Mar 25, 2011. #1. While many have already written on the subject of the so called “plateau sigma”, my own experience compels me to offer some input. My DXM use has varied over the years, from sparse to moderate to chronic and back again. DXM is a strange drug. At first it seems to be a sort of dirty, cheap ...Updated: Apr 30, 2024. Table of Contents. DXM (dextromethorphan) is a cough suppressant medication (antitussive) that has been on the market for many years. Originally released in the 1950s, it became highly abused and was removed from the consumer market.Jan 31, 2002. Messages. 1,433. Mar 25, 2011. #1. While many have already written on the subject of the so called “plateau sigma”, my own experience compels me to offer some input. My DXM use has varied over the years, from sparse to moderate to chronic and back again. DXM is a strange drug. At first it seems to be a sort of dirty, cheap ...Jun 26, 2023 · The dose for the second plateau is between 2.5 and 7.5 mg/kg. This works out to between 200 and 550 mg DXM. The second plateau is very different from the first. At this dose, the effects feel much more similar to alcohol but with a pronounced reduction in cognitive function. People at this stage feel drunk. Get ready to travel the world competing in Virtua Tennis 4. Check out this new trailer which shows the features of World Tour mode.IGN's YouTube is just a t... I did 3rd plateau many times and sometimes took larger amounts via a succession of doses or polistirex, I guess tending toward sigma. I only tried 4th plateau via one dose of DXM HBr once. In terms of getting interesting drug effects, it was a disappointment. DXM Calculators. A DXM calculator is an electronic or mechanical device that performs arithmetic computations to help users determine DXM dosages for desired plateaus. All listed values by dxm calculators are for reference only. Information produced by calculators may vary and is not guaranteed.2nd plateau DXM is like you drank a 6-pack of psychedelic beer. 6. [deleted] • 10 yr. ago. Second plateau will give you the characteristic robo-walk. You'll be stumbling for a while. It'll also be hard to visually focus on things. You may have some dreams or visions when you close your eyes; these are part of the dissociative effects of DXM. 3. I did 3rd plateau many times and sometimes took larger amounts via a succession of doses or polistirex, I guess tending toward sigma. I only tried 4th plateau via one dose of DXM HBr once. In terms of getting interesting drug effects, it was a disappointment. This is a difficult question to answer, because DXM’s effects tend to vary widely depending on the person, their set and setting, other drugs, their physiology, and so on. DXM, probably more than most drugs, tends to exert its (recreational) effects in separate stages or “plateaus”, rather than being linearly dose-dependent. Within a given plateau, a given …The fireworks end, everyone’s gone, and me and my friends are sitting around talking, I sit down and I’m starting to go fuzzy, like I’m fading out of reality. I manage to keep my cool for about a half hour. Then I see an ambulance and get paranoid so I want to leave.2nd plateau DXM is like you drank a 6-pack of psychedelic beer. 6. [deleted] • 10 yr. ago. Second plateau will give you the characteristic robo-walk. You'll be stumbling for a while. It'll also be hard to visually focus on things. You may have some dreams or visions when you close your eyes; these are part of the dissociative effects of DXM. 3.Sigma is not a secret plat or anything remotely worth striving for. It's literally DXM psychosis/overdose and can be incredibly dangerous and harmful to your body. There is no point to it and encouraging or helping others reach sigma can be a punishable offense. It's reckless and unnecessary. Most people who talk about 'sigma' in a positive ...Greenlighter. Dextromethorphan (DXM or DM) is a drug of the morphinan class with sedative, dissociative, and stimulant properties in higher doses. I drank 2 bottles of cough syrup DM Max, which has 30 milligrams of dextromethorphan Hbr per 10ml equating to approximately 720mg of DXM HBR per bottle. Took place in June of 2016.Trip Reports - DXM. 1000mg mg, a 14mg/kg dose, and floated thorough various alien landscapes, ... in retrospect i would say there are only two "regular" plateaus of dxm. the uppity weird high that is the mild at the first and stronger second, and being lost in your inner realities, which is a third plateau, and the fourth plateau is just a ...InvestorPlace - Stock Market News, Stock Advice & Trading Tips The news propelling the pupcoin frenzy just isn’t slowing down. Last week... InvestorPlace - Stock Market N... Second Plateau (200–400 mg) — Euphoria & hallucinations; Third Plateau (300–600 mg) — Profound distortions in visual & auditory perception; Fourth Plateau (500–1500 mg) — Complete dissociation & sedation; These plateaus and the effects of DXM will vary depending on the person. It depends on gender, body weight, and tolerance to the ... Large doses can cause dextromethorphan side effects, like emotional dissociation, hallucinations, or euphoria. There are four major DXM plateaus reported in dextromethorphan abuse: Plateau 1: 100 mg to 200 mg of DXM can lead to euphoria and restlessness. Plateau 2: 200 mg to 500 mg of DXM can bring about exaggerated …Dextromethorphan, or DXM, a common active ingredient found in many over-the-counter cough suppressant cold medicines, is used as a recreational drug and … Try a higher plat 2, till your comfortable with it. When sober focus on what's negative in your life, and aim to live a positive lifestyle. Then start at low plat 3 and watch some positive YouTube videos if you have to, listen to positive music, or lay down and contemplate why you have negative feelings while high (contemplate while high, think ... DXM Calculators. A DXM calculator is an electronic or mechanical device that performs arithmetic computations to help users determine DXM dosages for desired plateaus. All listed values by dxm calculators are for reference only. Information produced by calculators may vary and is not guaranteed.DXM Plateaus? I'm interested in trying DXM. Erowid has been a good source for dosage and what products I should buy and what I should avoid, though I've …Most DXM abusers ingest the drug orally, although some snort the pure powdered form of the drug. Abusers ingest various amounts of DXM depending on their body weight and the effect or plateau that they are attempting to achieve (see text box). Some abusers ingest 250 to 1,500 milligrams in a single dosage, far more than the recommended ...Now DXM is definitely my favorite drug. I have consumed it extensively in a variety of forms (powder, syrup, capsules) and always enjoy the effects greatly. When I started using this drug, I new nothing about the "plateaus", the DXM FAQ, or any other real info on the drug (except that avoiding syrups with other active ingredients was the way to ...No. If you have to take Anti Depression Medicine (SSRIs, SNRIs) you can NOT take DXM (not even in small doses). You WILL get very negative effects and their is a VERY high chance you will get Serotonin Syndrome which is life threatining (here are some symptoms: High fever, Seizures, Irregular heartbeat, Unconsciousnes etc.)Introduction. Dextromethorphan hydrobromide (DXM HBr) is a semi-synthetic opioid sharing N-methyl-d-aspartate receptor antagonistic properties with its primary metabolite, dextrorphan, but lacking significant analgesic properties.It is available over the counter and is commonly used recreationally for its NMDA receptor antagonism and …WebMD explains that the biggest risk from drinking too much cough syrup is overdose on DXM, a common ingredient in nearly all over-the-counter cough medicines.I am reading up on DMX and am confused on how they work. Do you take a high dose and reach the third plateu, or do you dose once and and once you are…I felt as though I had a connection with God, one that I had never before had. Imagine the numbers 1 through 10, 1 being no DXM at all, and 10 being a fatal overdose of DXM...All numbers greater than 1 bring you that much closer to death, and in that, bring you that much closer to God. The upper plateaus are most definitely meant for spirituality.Be careful with your dosing with this product - this is DXM FREEBASE, and it is MUCH stronger than store bought DXM HBr or DXM Polistirex. My personal ...14-Apr-2022 ... An attempt to replicate the closed eye visuals of lower second plateau DXM trips and dissociatives like Ketamine and PCP derivatives. DXM seems to exhibit at least four definable plateaus based solely on dosage, and an additional plateau sigma is notable from a specific dosing regimen. Not everyone notes distinction between the first and second plateaus, or between the third and fourth plateaus. DexCalc uses modified values for some ratios due to problems on Darkridge where the reccomended dose for a plateau would be outside the range of that plateau (i.e. Reccomended 3rd would be beyond the 3rd max and beyond the 4th min). If you would like you can compare the page source code for Darkridge and DexCalc! DXM Plateaus. Abusers describe the DXM experience as occurring on four different plateaus. Abusers ingest increasing amounts of DXM (based on their weight) to reach each succeeding plateau. Abusers report the following effects occurring in each plateau: First Plateau: Mild inebriation. Dxm is not a dumb kids/irresponsible persons drug though. There is an active community who take it safely and responsibly, and for a legal drug it is extremely powerful and not to be fucked with lightly. ... We do about 450 mg (a bottle of robocough) every couple months or so , and it's a comfortable to high 2nd plateau depending on how our ...Dextromethorphan (DXM) is a cough suppressant used in many cough and cold medicines. It affects serotonin, norepinephrine, NMDA, and sigma-1 receptors in the brain, all of which have been implicated in the pathophysiology of depression.In 2022, the FDA approved the combination dextromethorphan/bupropion to serve as a rapid acting …Jan 31, 2002. Messages. 1,433. Mar 25, 2011. #1. While many have already written on the subject of the so called “plateau sigma”, my own experience compels me to offer some input. My DXM use has varied over the years, from sparse to moderate to chronic and back again. DXM is a strange drug. At first it seems to be a sort of dirty, cheap ...Archived post. New comments cannot be posted and votes cannot be cast. The 3rd plat is full of vivid closed-eye visuals, derealization, memory issues, looping, and delusions. Amnesia, retardation, vertigo or changes in the direction of gravity, mild dark CEVs and visual noise is the only OEV. favorite thing to do is listen to music with eyes ...Abusers of DXM describe the following three dose-dependent “plateaus”: What is its effect on the body? DXM intoxication involves: • Over-excitability, lethargy, loss of coordination, slurred speech, sweating, hypertension, nausea, vomiting, and involuntary spasmodic movement of the eyeballs The use of high doses of DXM in combination withLarge doses can cause dextromethorphan side effects, like emotional dissociation, hallucinations, or euphoria. There are four major DXM plateaus reported in dextromethorphan abuse: Plateau 1: 100 mg to 200 mg of DXM can lead to euphoria and restlessness. Plateau 2: 200 mg to 500 mg of DXM can bring about exaggerated …New comments cannot be posted and votes cannot be cast. A 3oz delsym. Take the normal dose of dxm multiplied by 2. It depends on your weight entirely. Go to: https://dxm.tripsit.me/. It’s a dex calculator, it factors in your weight and what product you are choosing to use so that you know what to expect. For a good/moderate trip you need to ... DXM acts as a dissociative drug when taken at doses higher than what is recommended in cough medicines. 1 It is described as having more psychedelic effects than other dissociatives (such as ketamine or PCP) and its effects depend heavily on the dosage. 1 DXM is commonly categorised into four or five dose “plateaus” where the effects are ... 600 - 1500 mg. Risk of Death. 2,500 - 20,000 mg 1. Duration : 4 - 8 hours (DXM HBR) Duration (extended release) : 6 - 12 hours (DXM Polistirex) Some users report that DXM dosages are affected significantly by bodyweight and lighter users should start with lower dosages. Because everyone reacts differently, it is a better idea to start at lower ... Anyways, after months and months of positive experiences with DXM in 1st-3rd Plateau, I decided that I felt confident enough to experiment in higher doses. I don't remember what I was doing the exact day I reached my 4th Plateau DXM Trip but I do remember most of the effects since I triped on 4th Plateau for 2+ years after my first experience. 3rd plateau: At this level, you won't be moving much. If you need to get up for a drink of water or to take a piss, you probably still can, but it's going to take you about five times longer than usual to do that. Your body won't be very responsive anymore. For that reason, it's a safe practice to prepare during the comeup.DXM acts as a dissociative drug when taken at doses higher than what is recommended in cough medicines. 1 It is described as having more psychedelic effects than other …Get ready to travel the world competing in Virtua Tennis 4. Check out this new trailer which shows the features of World Tour mode.IGN's YouTube is just a t...Um die Dosierung zu berechnen, nutze bitte den DXM-Rechner. Dabei oben das Gewicht in Kilogramm angeben und Pures DXM (mg) auswählen. Den gewünschten Wert dann durch 22 teilen, da es sich beim Hustenstiller um das DXM-HBr handelt, 100 mg DXM-HBr entsprechen 77mg DXM. Nun hast Du die Anzahl der Kapseln. Plateau #1.A 39-year-old woman was abducted shortly after deplaning her flight to Bangkok. She was abducted in the middle of the secure area of the 20th busiest airport in the world. Shortly ...Dextromethorphan (also known as robo, dex, DM, and DXM) is a dissociative substance of the morphinan class. It is the …Australian scientists have devised a way to pinpoint the causes of the global die-off of bees that pollinate a third of the world’s crops: Attach tiny sensors to 5,000 honey bees, ... The lower DXM plateaus seem to show a number of differences from other dissociatives. This is most likely due to DXM's unique potency at the dopamine reuptake site (the PCP 2 receptor) and the sigma receptor. DXM's ability to block dopamine reuptake is probably the biggest factor in its popularity at lower plateaus; neither ketamine nor PCP ... Some people start collecting because of a particular fascination. Others stumble into the hobby, perhaps through an inheritance, a lucky find, or even a gift. And still others find...DXM Plateau Sigma Report Prefix: I had a lot of experience with various psychedelics and dosages, but I used DXM only twice prior to investigated the infamous 'Sigma Plateau'. The two times I used 300mg and 350mg doses. When I read about Sigma I thought to myself: 'Damn, I really have a chance to be in places only a few 'chosen ones' have been to'.DXM in the lower two plateaus has been compared to a cross between MDA and alcohol. It tends to intensify emotional responses and feelings of meaning from external events. At the lower plateaus there is usually enough motor control to be able to engage in physical activites (although, like MDMA and MDA there are reasons why you may not want to ...New comments cannot be posted and votes cannot be cast. A 3oz delsym. Take the normal dose of dxm multiplied by 2. It depends on your weight entirely. Go to: https://dxm.tripsit.me/. It’s a dex calculator, it factors in your weight and what product you are choosing to use so that you know what to expect. For a good/moderate trip you need …An Experience with DXM. 'The Fifth Plateau' by r e d h e a v e n. The Fifth Plateau. DXM. by r e d h e a v e n. ... but man, I was flying by plateaus like it was yesterday. The fireworks end, everyone’s gone, and me and my friends are sitting around talking, I sit down and I’m starting to go fuzzy, like I’m fading out of reality.The DXM Trip Calculator is based on a straightforward formula that calculates the recommended dosage based on a person’s body weight. The formula is as follows: First Plateau (Mild effects): 1.53-2.5 mg per kg of body weight. Second Plateau (Moderate effects): 2.5-7.5 mg per kg of body weight.14-Apr-2022 ... An attempt to replicate the closed eye visuals of lower second plateau DXM trips and dissociatives like Ketamine and PCP derivatives.DXM Plateaus (There is no "5th plateau," guys) Discussion So lately I've been seeing a lot of casual mentions of a 5th plateau, people on the sub seem to be picking this up and running with it. I'd like to stop this particular train before it leaves the station, so I'll say it as plainly as I can: the 5th plateau does not exist. There ...Perhaps the perimeters of the first and second plateaus aren't precisely defined. The primary point is that if the first plateau was its own drug, it would be a good one that I and others would do, and that experiencing the strongest DXM trip that you can bear isn't the only way to do it. 1600mg of DXM, the Fourth Plateau, and a trip to the hospital. On the evening of Wednesday, August 29th, I consumed 1776mg of Dextromethorphan Polisterix. (2 5 Oz Bottles of Delsym) I also consumed 300mg of Dextromethorphan HBr. (20 Robitussin cough gels). These dosages were spaced out throughout the evening, to avoid nausea as much as possible. Questions about Plateaus and levels of dosage. First question, do different doses within the same plateau adjust the effects of it? Example: when I first tried dex, I did 300mg, and I would describe it as a drunk body feeling while being pretty clear-headed. And I only noticed very little effect from listening to music and such.Pulse (92-162bpm) and blood pressure tended to be high, muscle tone flaccid. HGN and VGN typically present, often resting nystagmus, droopy eyelids, red eyes. The popular practice of dextromethorphan abuse results in driving impairment. Signs of impairment are often a result of combined DXM dissociative and depressant effects. Um die Dosierung zu berechnen, nutze bitte den DXM-Rechner. Dabei oben das Gewicht in Kilogramm angeben und Pures DXM (mg) auswählen. Den gewünschten Wert dann durch 22 teilen, da es sich beim Hustenstiller um das DXM-HBr handelt, 100 mg DXM-HBr entsprechen 77mg DXM. Nun hast Du die Anzahl der Kapseln. Plateau #1.

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dxm plateus

Facebook will bring the Oculus Go to China thanks to a partnership with hardware giant Xiaomi. On Jan. 8 at CES in Las Vegas, VR company Oculus announced it will form a partnership...DXM Calculators. A DXM calculator is an electronic or mechanical device that performs arithmetic computations to help users determine DXM dosages for desired plateaus. All listed values by dxm calculators are for reference only. Information produced by calculators may vary and is not guaranteed.In other words, Dextromethorphan. It is the best drug ever created.Second plateau – at 250 mg to 400 mg, euphoria heightens and perception of time and space changes; Third plateau – 450 mg to 800 mg, visual distortions; Fourth and fifth plateaus – doses of 800 mg to 1,800 mg and more can be extremely harmful; Purple Drank. DXM was approved by the FDA in 1958 and there was early evidence of extensive abuse.If the portfolio of a corporate venture capital firm can be taken as a signal for the strategic priorities of their parent companies, then National Grid has high hopes for automati... DXM Dosage Calculator. This is a simple calculator designed to help you discern how much DXM you need to take reach each plateau of experience, depending on variable factors such as your weight and concentration of the product you're using. For a description of the plateau model, and the effects you can expect at each level, click here. NSFW. 1st time and thinking about going straight to the 3rd plateau. Newbie. I never intended on using this as a social drug, so when I did some research it said that all of the social aspects of DXM go down the hatch on the third plateau that's when I decided that I was going straight there. I am going to use 40 Delsym fast release pills 15mg ... But if you're worried, take two pills and then the other two like 20 mins later. That should guarantee no nausea. 4 robo tabs you should have 0 nausea and should still have a really fun time, thats what i took last Friday and i weigh more, and i have a slight tolerance and it still felt good kinda like a low dose of mdma.600 - 1500 mg. Risk of Death. 2,500 - 20,000 mg 1. Duration : 4 - 8 hours (DXM HBR) Duration (extended release) : 6 - 12 hours (DXM Polistirex) Some users report that DXM dosages are affected significantly by bodyweight and lighter users should start with lower dosages. Because everyone reacts differently, it is a better idea to start at …There’s a lot to be optimistic about in the Financial sector as 2 analysts just weighed in on Sun Life Financial (SLF – Research Report) a... There’s a lot to be optimistic a...TripSit DXM Calculator Tool. DXM Dosage Calculator. This is a simple calculator designed to help you discern how much DXM you need to take reach each plateau of experience, …Who would write an anonymous essay that undermines their boss and their own country's stability? In the Trump administration, there are plenty of suspects. The US director of natio...Greenlighter. Dextromethorphan (DXM or DM) is a drug of the morphinan class with sedative, dissociative, and stimulant properties in higher doses. I drank 2 bottles of cough syrup DM Max, which has 30 milligrams of dextromethorphan Hbr per 10ml equating to approximately 720mg of DXM HBR per bottle. Took place in June of 2016.Jul 17, 2013. #1. Warning: The dosages mentioned below are on the extreme side. reaching the 4th plateau and/or sigma on dxm is not safe & although I have done exactly what I will describe many times without any harm done, that does not mean you will, do not try this at home. So, despite what some may think, reaching the 4th plateau & also ...Abstract. Dextromethorphan (DXM) is a safe and effective antitussive agent present in several over the counter cough and cold medications. At higher doses, it causes psychoactive effects, making it appealing for abuse. In this work, the pharmacokinetics and pharmacodynamics of DXM with clinical and forensic relevance were extensively reviewed..

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