Abstract. Fenbendazole remains the drug of choice to treat pinworm infection in laboratory rodents. When fenbendazole was last reviewed (15 y ago), the literature supported the drug's lack of toxic effects at therapeutic levels, yet various demonstrated physiologic effects have the potential to alter research outcomes.Risks and Side Effects of Fenbendazole. Benzimidazole anthelmintics are used in both human and veterinary medicine. Decades of use since their introduction in the 1960s has shown them to be well-tolerated without severe side-effects in most species, which provides a basis for potential safety of fenbendazole in humans [3].Panacur for dogs is made using fenbendazole, an extremely safe medicine. However, 1% of dogs experienced the side effect of vomiting during clinical trials.Aug 3, 2021 · The drug gets into the parasite’s gut and collapses the tubulin, starving the parasite to death. The study shows that mebendazole may act similarly in pancreatic cancer by collapsing cancer cells’ structure, along with other mechanisms such as reducing inflammation. Riggins says he hopes to continue his team’s research through human ... Abstract. Fenbendazole remains the drug of choice to treat pinworm infection in laboratory rodents. When fenbendazole was last reviewed (15 y ago), the literature supported the drug's lack of toxic effects at therapeutic levels, yet various demonstrated physiologic effects have the potential to alter research outcomes.Fenbendazole History. 📄 5 mins. Dr. Gregory Riggins lab at John Hopkins was known for researching gene mutations that cause cancer as well as for developing new medications in the preclinical setting before suggesting them for further clinical trials. In most of the cases, the researcher and his colleagues had no trouble inducing ...The Freedom of Information Act gives citizens access to government materials, but not every document is made public. Learn more at HowStuffWorks. Advertisement U.S. Rep. John Moss,...In a blog post Wednesday, Elon Musk detailed his vision. By clicking "TRY IT", I agree to receive newsletters and promotions from Money and its partners. I agree to Money's Terms o...Exploring the Potential Side Effects of Fenbendazole in Cats. As with any medication, fenbendazole may have some potential side effects, although they are usually rare and mild. It’s important to be aware of these possible side effects to ensure the well-being of your feline companion. What to Watch Out for When Administering Fenbendazole to CatsPrecautions and Side Effects. While generally safe and effective when prescribed by a veterinarian, fenbendazole can cause side effects in some animals. Fenbendazole should not be used in animals with known hypersensitivity or allergy to the drug. Infrequently, vomiting can occur after administration. The presence of dead worms in the stool may ...Cancer is the most commonly diagnosed type of disease and a major cause of death worldwide. Despite advancement in various treatment modules, there has been little improvement in survival rates and side effects associated with this disease. Medicinal plants or their bioactive compounds have been extensively studied for their anticancer …Ventricular assist devices (VADs) help your heart pump blood from one of the main pumping chambers to the rest of your body or to the other side of the heart. These pumps are impla...First introduced in 1974, fenbendazole is now distributed worldwide. Besides eliminating parasites, studies reveal fenbendazole also shows promise as an anti-cancer agent. So far, some doctors have witnessed fenbendazole yield positive outcomes for patients with minimal side effects.Artesunate injection is used to treat severe malaria. This medicine is also used together with other medicines (eg, 8-aminoquinoline medicine) to treat severe malaria caused by Plasmodium ovale or Plasmodium vivax. Artesunate belongs to a group of medicines known as antimalarials. It treats malaria, a red blood cell infection transmitted by the ...Sep 15, 2015 · For example, when they tested very large doses on cats, they found no detectable side effects. Its chemical formula is C15H13N3O2S. How does fenbendazole kill parasites? Fenben’s safety for humans stems from its mode of action – it binds to 3-tubulin astructural protein that blocks polymerization of tubulin into microtubules. Got that? It’s hard to say if CBD oil can alleviate cancer symptoms or cancer treatment side effects, because the studies are pretty mixed and even fewer are standardized. There have been reports that cannabinoids like THC and CBD may be helpful for nausea and vomiting and anorexia, as well as neuropathy, anxiety, depression and insomnia.Heal Navigator is the largest resource for alternative cancer clinics and alternative cancer treatments. Learn more about us here.If Fenben Lab or another recognized manufacturer doesn’t produce it, pump your brakes! ... Monitor for side effects: Like any other drug or treatment, monitoring for potential side effects is ...The Fenben Foundation and its informational resources are not intended to provide personal medical advice. Always consult your physician before beginning any protocols. No information on this site is intended to diagnose, treat, or otherwise replace the opinion of medical professionals. The purpose of this site is for informational purposes ONLY.Effects of Fenbendazole on the expression of virion-associated proteins. (A, D) MDBK cells were infected with BoHV-1 at an MOI of 1 for 12 and 24 h, in the presence of fenbendazole or DMSO control throughout infection plus a pretreatment for 1 h. The cell lysates were then prepared for Western blots to detect viron-associated proteins using a ...The Fenben Foundation and its informational resources are not intended to provide personal medical advice. Always consult your physician before beginning any protocols. No information on this site is intended to diagnose, treat, or otherwise replace the opinion of medical professionals. The purpose of this site is for informational purposes ONLY.Effects: Gutworm can cause severe damage to the stomach and small intestine which will cause parasitic gastroenteritis, this will not only negatively affect the ...While inflammation is a natural response of the immune system and needed to overcome infection, it can, in the short term, lead to symptoms like aches and pains, skin rashes, headaches, etc, which we often describe as die-off. 3. Detox. All of the broken down biofilm and released toxins need to go somewhere.May 13, 2019 ... It also interferes with cancer cells abilities to use glucose. One study showed a cumulative/synergistic effect when combined with taxol, since ...Jun 17, 2014 · Side Effects. In horses, no side effects for a single dosage as high as 454 mg/lb were noted. Mutliple doses of 22.7 mg/lb were also administered on 15 consecutive days without side effects. In rare cases, antigens produced by the dying parasites may result in either a local or systemic hypersensitive reaction. Precautions Potential Side Effects: a. Gastrointestinal Effects: Some individuals have reported mild gastrointestinal side effects when taking fenbendazole. These may include nausea, vomiting, diarrhea, or abdominal discomfort. These symptoms are typically transient and resolve on their own. If persistent or severe, it is important to consult a healthcare ...Cabozantinib was ultimately discontinued due to persistent intolerable side effects. One month after discontinuation, repeat MRI showed increase in size of recurrent left renal mass, mild decrease in 2.3 cm pancreatic head lesion, stable 1.4 cm distal pancreatic body lesion, and unchanged 1.1 cm right posterior iliac bone lesion.May 16, 2023 ... 66yo wm, stage 4 Prostate cancer last PSA >1750, 1.5 months later 1250 on my protocol my PSA dropped 500 points! Two months ago I was ...Anti-cancer effects of fenbendazole in colorectal cancer cells. (A) The SNU-C5 and 5-FU-resistant SNU-C5 (SNU-C5/5-FUR) cells were mock-treated with dimethyl sulfoxide (DMSO) or treated with indicated concentrations of fenbendazole or albendazole for 3 days. The extent of cell viability was determined by MTT assay as described in Methods.Fenbendazole, a dewormer drug, is used widely in the clinical treatment of parasite infections in animals. Recent studies have shown that fenbendazole has substantial effects on tumor growth, immune responses, and inflammatory responses, suggesting that fenbendazole is a pluripotent drug. Nevertheless, the antiviral effects have not been reported.Potential Side Effects: a. Gastrointestinal Effects: Some individuals have reported mild gastrointestinal side effects when taking fenbendazole. These may include nausea, vomiting, diarrhea, or abdominal discomfort. These symptoms are typically transient and resolve on their own. If persistent or severe, it is important to consult a healthcare ...Jan 1, 2020 ... NO side effects!! After taking all the AIs and Capecitabine ( over 5 1/2 years) I was started on Abraxane (chemo infusion) in June ... Sept ...Apr 7, 2023 · One of the more common side effects of ARBs is dizziness. Calcium Channel Blockers (CCBs) These high blood pressure medications keep calcium from entering heart muscle and blood vessel cells ... However, if you notice any severe or persistent side effects, it’s crucial to consult your veterinarian immediately. Moreover, in rare cases, certain cats may be hypersensitive to fenbendazole, leading to more severe allergic reactions. Symptoms of an allergic reaction can include swelling, difficulty breathing, or skin rashes. An accurate estimate of the prevalence of Aspiculuris tetraptera and Syphacia spp. infection in rats and mice is not available for recent years, but these agents likely remain problematic for many animal facilities despite effective treatment regimens using fenbendazole-medicated diets. 6,7,9,39,52 Although many facilities may still depend on microscopic examination of fecal floats and tape ... pains in the stomach, side, or abdomen, possibly radiating to the back. pale skin. swelling of the face, fingers, or lower legs. upper right stomach pain. weight gain. Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine.I am currently taking xtandi, started easy , knowing the bad side effects, started 1 a da first week, 2 a day 2 so the 3rd week 3 a day every other day. So far I feel pretty good, kinda reluctant to take more. I hzve bone mets and my r hip wss hurting prior to xtandi and fenben. There's still much to learn about its effects on humans, particularly in advanced stages of illness. The sudden changes you observed, like the loss of voice and fever, could be related to her overall health condition rather than the fenbendazole. However, in such complex situations, certainty is often elusive. Are there any potential side effects? At regular doses, fenbendazole does not usually cause any side effects. Sometimes, substances released by the dying parasites may cause an allergic reaction, especially if fenbendazole is given at higher than regular doses.Side effects of fenbendazole for dogs is rare. However, some dogs may experience gastrointestinal problems such as upset stomach, vomiting and diarrhea. Increased salivation is also possible. Certain fenbendazole formulations, like Panacur Plus, contain other medications, such as ivermectin and praziquantel, which may produce more severe …MMS can cause an array of side effects that vary in severity. The FDA reported receiving recent accounts of MMS users experiencing severe vomiting, severe diarrhea and life-threatening low blood pressure due to dehydration. There have even been cases of acute liver failure after drinking MMS. Although MMS sellers claim the solution is ...However, the group supplemented with both vitamins and fenbendazole exhibited significant inhibition of tumor growth. The mechanism for this synergy is unknown and deserves further investigation. Fenbendazole should be used with caution during tumor studies because it may interact with other treatments and confound research results.Airlines for America expects far fewer flyers this Thanksgiving than in years past, eschewing its traditional forecast in light of the uncertainty during the coronavirus pandemic. ...Sep 5, 2023 · Fenben interrupts the ongoing cycle by specifically targeting the mature roundworms residing in the intestines, essentially starving these worms to death. This approach is gentle but effective, reducing potential side effects that might happen when treating a heavy roundworm load using other medications. nosebleeds. pale skin. puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue. redness of the skin. sore throat. sweating. trouble breathing or swallowing. Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.Side effects include vomiting and diarrhea, although both are considered rare. Fenbendazole is not approved for use in cats in North America but is commonly used clinically, and an empirical dosage of 50 mg/kg orally every 24 hours for 5 consecutive days is recommended.When markets are at record highs as we face maximum risk, investors should consider ways to hedge your portfolio of stocks. Luke Lango Issues Dire Warning A $15.7 trillion tech mel...Worldwide, veterinarians commonly use fenbendazole, FBZ, to treat a variety of parasites in animals, such as tapeworms, hookworms, roundworms, lungworms, and whipworms. Fenbendazole has been known to have a high safety margin for animal use as it is tolerated well, has low side effects, and has a low degree of toxicity.Serious side effects of Briviact. Along with its needed effects, brivaracetam (the active ingredient contained in Briviact) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while ...Aug 9, 2018 · Combination effect of FZ with other drugs. Finally, we evaluated the effect of FZ in combination with the microtubule targeting drug taxol, glycolytic inhibitor 2 deoxyglucose (2DG) and dichloroacetate (DCA) - a pyruvate dehydrogenase kinase inhibitor which acts by shifting the metabolism towards glucose oxidation over glycolysis. Fenbendazole is an antiparasitic drug commonly used to treat parasites (heart worm in dogs and other parasites in humans). There is some promising evidence in studies with mice and rats re: enhancing the effectiveness of chemo in treating breast cancer. There are currently no clinical trials with humans. Ivermectin, another …Fenbendazole is a benzimidazole that presents a wide spectrum anthelmintic effect. It is used against a number of gastrointestinal parasites including giardia, roundworms, hookworms, whipworms, the Taenia genus of tapeworms, pinworms, aelurostrongylus, paragonimiasis, strongyles, and Strongyloides. Fenbendazole is approved to be …Regular doses of fenbendazole rarely cause side effects in dogs. Toxicity or drug overdose is also rare. However, continue to be on the lookout for a few adverse effects such as: Nausea; Vomiting; Diarrhea; Excessive salivation; Veterinarians may prescribe combination anthelmintics that include fenbendazole and other active ingredients.Fenbendazole for humans side effects. One of the most common side effects to monitor is the liver enzyme level, which can become elevated while taking fenbendazole. Therefore, patients need to get a frequent blood count while taking fenbendazole and participating in the fenben protocol.Enjoy the videos and music you love, upload original content, and share it all with friends, family, and the world on YouTube. There's still much to learn about its effects on humans, particularly in advanced stages of illness. The sudden changes you observed, like the loss of voice and fever, could be related to her overall health condition rather than the fenbendazole. However, in such complex situations, certainty is often elusive. First introduced in 1974, fenbendazole is now distributed worldwide. Besides eliminating parasites, studies reveal fenbendazole also shows promise as an anti-cancer agent. So far, some doctors have witnessed fenbendazole yield positive outcomes for patients with minimal side effects.The agent is also reported to exert antitumor effects and inhibit microtubule-associated tubulin polymerization, but its safety and tolerability profile in humans remains unclear. An 80-year-old female patient with advanced nonsmall cell lung cancer (NSCLC) was started on pembrolizumab monotherapy. The patient experienced severe liver injury …Jun 27, 2021 ... for example do you have any. side effects that you you noticed. i've never had any and. um. ninety. to ninety five percent of the people do not.Fenbendazole and Joe Tippens Fenbendazole or FenBen is a dewormer or anthelmintic in the family of drugs called benzimidazoles( I coined it Benz), which have been safely used as anthelmintics for roughly six decades. Broad-spectrum anthelmintics comprise three main groups (benzimidazoles [BZ] and probenzimidazoles, imidazothiazoles and …The next day of consumption, the Fenben will kill again half of the four remaining cells, and after days 3 or 4 most of these stem cells will be gone and the small intestine will be dangerously damaged, indicated by numerous side effects such as vomiting and cramps. Fenben users (for treating themselves or pets) have probably …Q: Did you notice any side effects that might be attributable to the fenben? A: Zero so far. My liver enzymes (measured every 3 months) are actually on the low side, and did not increase even 1% - some may have even decreased a bit- since starting FenBen. I have plenty of drug side effects, but they were all present long before I started FenBen.Some people taking over 1,500 mg per day of TUDCA supplements experienced diarrhea, but no other side effects have been reported. Key Takeaways. Tauroursodeoxycholic acid (TUDCA) is a naturally-occurring bile acid that has been used for thousands of years as a supplement for its many health benefits.The effects of the significant interaction between treatment and sample number in the LCAFEC model varied over time. There was a significant difference between treatment groups at some sample numbers, but not others; the rank order for mean LCAFEC varied by treatment and time (i.e., sample number).Tamoxifen side effects may include: Menopause-like symptoms, including hot flashes, night sweats and vaginal dryness. Weight gain (more common) or fluid retention ( edema ). Irregular or loss of menstrual periods. Leg swelling.This Study Summary was published on April 4 2021. Some evidence suggests that taurine supplementation may increase lipid metabolism during high-intensity exercise, potentially resu...Although anti-cancer effects of fenbendazole as an alternative or supplementary agent were recently reported in a case series of genitourinary …Fenbendazole for Humans – Side Effects. Some research suggests that those who are weak from chemotherapy may experience more side effects than those not receiving conventional cancer treatment. Some common side effects that have been reported include elevated liver enzymes, mild diarrhea, and mild stomach discomfort.The combination of Ivermectin and paclitaxel has a synergized effect on ovarian cancer. A combined treatment of these two almost completely inhibited tumor growth in vivo. Ivermectin and colon cancer Ivermectin has been shown to have anti-virus, anti-inflammatory, and antitumor properties when it comes to colorectal cancer. …Exploring the Potential Side Effects of Fenbendazole in Cats. As with any medication, fenbendazole may have some potential side effects, although they are usually rare and mild. It’s important to be aware of these possible side effects to ensure the well-being of your feline companion. What to Watch Out for When Administering Fenbendazole to CatsThe next day of consumption, the Fenben will kill again half of the four remaining cells, and after days 3 or 4 most of these stem cells will be gone and the small intestine will be dangerously damaged, indicated by numerous side effects such as vomiting and cramps. Fenben users (for treating themselves or pets) have probably …I am currently taking xtandi, started easy , knowing the bad side effects, started 1 a da first week, 2 a day 2 so the 3rd week 3 a day every other day. So far I feel pretty good, kinda reluctant to take more. I hzve bone mets and my r hip wss hurting prior to xtandi and fenben.I too, saw Fenben lab, and i agree somewhat with Daniel in one way but not another. You see, i refuse to take any Pharmaceutical drugs due to their serious side effects. So i go for alternative type medicine if i can, but yes, I did look at the reviews, and one did state THIS IS NOT TRUE FENBENDAZOLE, although i thought that in the first …Fenbendazole History. 📄 5 mins. Dr. Gregory Riggins lab at John Hopkins was known for researching gene mutations that cause cancer as well as for developing new medications in the preclinical setting before suggesting them for further clinical trials. In most of the cases, the researcher and his colleagues had no trouble inducing ...Along with its needed effects, semaglutide (the active ingredient contained in Ozempic) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking semaglutide: More common. …Heal Navigator is the largest resource for alternative cancer clinics and alternative cancer treatments. Learn more about us here.Fenbendazole is a potent anthelmintic medication, specifically designed to combat various intestinal parasites that can affect dogs, such as nematodes. Its trade names include Panacur® and Safe-Guard®. Nematodes are helminths, or parasitic worms, that include roundworms, hookworms, and whipworms. While it has labelled claim to treat and ...It isn’t a cure, but it may help improve symptoms. Common side effects of Aricept include nausea, diarrhea, trouble sleeping, muscle cramps, and low appetite. For …For example, when they tested very large doses on cats, they found no detectable side effects. Its chemical formula is C15H13N3O2S. How does fenbendazole kill parasites? Fenben’s safety for humans stems from its mode of action – it binds to 3-tubulin astructural protein that blocks polymerization of tubulin into microtubules. Got that?Interestingly, a previous hype around FB has caused the disappearance of much internet information about side-effects and modes of action of FB, presumably by a concerted action of manufacturers afraid of off-label use of FB in humans. ... No bad side effects from fenben, that I can see. There is a facebook page devoted to it, and you …Fenbendazole is generally considered safe when used as directed by a veterinarian. However, some dogs may experience mild side effects, including: Gastrointestinal Upset: The most common side effect is mild gastrointestinal upset. This may include symptoms like vomiting, diarrhea, or a temporary loss of appetite.For example, when they tested very large doses on cats, they found no detectable side effects. Its chemical formula is C15H13N3O2S. How does fenbendazole kill parasites? Fenben’s safety for humans stems from its mode of action – it binds to 3-tubulin astructural protein that blocks polymerization of tubulin into microtubules. Got that?Mebendazole is used to treat infections caused by worms. It works by keeping the worm from absorbing sugar (glucose), so that the worm loses energy and dies. This medicine is available only with your doctor's prescription. This product is available in the following dosage forms: Tablet, Chewable.Human Side Effects. Fenbendazole is a prescription veterinary medication not intended for use in humans. Wash your hands after handling this medication. Due to possible side effects, humans should never use medicine dispensed for their pets and pets should not be given any medicine dispensed for a human’s use.Fenbendazole was originally designed to cure parasites by selectively blocking the synthesis of microtubules by binding to β-tubulin. This stops the polymerization of tubulin dimers in cells of parasites and causes parasite death. Surprisingly, it seems that fenbendazole as well as other benzimidazoles exhibit a similar effect against tumor ...
The rates of melanoma have been rising rapidly over the past few decades, but this has varied by age. Melanoma is more than 20 times more common in whites than in African Americans. Overall, the lifetime risk of getting melanoma is about 2.6% (1 in 38) for whites, 0.1% (1 in 1,000) for Blacks, and 0.6% (1 in 167) for Hispanics.. Nyse aprn
A section for information hungry enthusiasts. 1) Fenbendazole acts as a moderate microtubule destabilizing agent and causes cancer cell death by modulating multiple cellular pathways. 2) Unexpected Antitumorigenic Effect of Fenbendazole when Combined with Supplementary Vitamins. 3) Fenbendazole as a Potential Anticancer Drug.However, this drug has some side effects, including gastrointestinal disturbances, hypersensitivity reactions, and retinal damage. Quinacrine. Quinacrine (QN) is another quinoline-based antimalarial drug studied as an anticancer agent. QN inhibits tumor growth in mouse xenograft models of liver and breast cancer.The agent is also reported to exert antitumor effects and inhibit microtubule-associated tubulin polymerization, but its safety and tolerability profile in humans remains unclear. An 80-year-old female patient with advanced nonsmall cell lung cancer (NSCLC) was started on pembrolizumab monotherapy. The patient experienced severe liver injury …First introduced in 1974, fenbendazole is now distributed worldwide. Besides eliminating parasites, studies reveal fenbendazole also shows promise as an anti-cancer agent. So far, some doctors have witnessed fenbendazole yield positive outcomes for patients with minimal side effects.Public Service Loan Forgiveness (PSLF) is a program that's helped many educated people to focus on public service. But there will be changes. This is a question I’ve been getting a...Several widely used anticancer drugs produce their antineoplastic effects by disrupting either microtubule formation (vincristine; vinblastine) or microtubule …Fenbendazole binds beta-tubulin subunits of microtubules, interfering with their polymerization. Side effects include vomiting and diarrhea, although both are considered rare. Fenbendazole is not approved for use in cats in North America but is commonly used clinically, and an empirical dosage of 50 mg/kg orally every 24 hours for 5 consecutive ...Panacur is the brand name of an oral deworming medication with the active ingredient fenbendazole. It is used to treat internal parasites in domestic animals, including dogs, cats, horses, and ...Tamoxifen side effects may include: Menopause-like symptoms, including hot flashes, night sweats and vaginal dryness. Weight gain (more common) or fluid retention ( edema ). Irregular or loss of menstrual periods. Leg swelling.May 16, 2023 ... 66yo wm, stage 4 Prostate cancer last PSA >1750, 1.5 months later 1250 on my protocol my PSA dropped 500 points! Two months ago I was ...Fennel (Foeniculum vulgare) is an herb with yellow flowers. The dried seeds are used in food. The dried seeds and oil are also used as medicine. Fennel is native to the Mediterranean, but is now ...What to do when medication makes you sleepy. It may be as simple as adjusting the dose, avoiding alcohol, or taking the drug at a different time of day. Image: iStock. One of the most commonly reported side effects of some medications is drowsiness. "Many people report tiredness or fatigue as a side effect from their medicines.Patient was staged as stage Iva, and was offered chemotherapy, but he declined treatment due to side effect profile. He started to take fenbendazole 1g daily based on self-research (used to take between 1-6 tabs daily based on his symptoms). After 6 months, he cut down fenbendazole to 1-3 tabs daily due to peripheral neuropathy. ...Fenbendazole is a broad-spectrum antiparasitic medication that is used to treat gastrointestinal parasites in animals. It can cause …The combination of Ivermectin and paclitaxel has a synergized effect on ovarian cancer. A combined treatment of these two almost completely inhibited tumor growth in vivo. Ivermectin and colon cancer Ivermectin has been shown to have anti-virus, anti-inflammatory, and antitumor properties when it comes to colorectal cancer. …Fenbendazole was originally designed to cure parasites by selectively blocking the synthesis of microtubules by binding to β-tubulin. This stops the polymerization of tubulin dimers in cells of parasites and causes parasite death. Surprisingly, it seems that fenbendazole as well as other benzimidazoles exhibit a similar effect against tumor ...Panacur Suspension is FDA approved for horses, cattle, and goats. Life Stage: Fenbendazole is commonly used for all life stages. Brand Names: Panacur, Safe-Guard. Common Names: Fenbendazole. Available Dosages: Granules (powder): 22mg/g in 0.18oz, 1g (10lb), 2g (20lb), and 4g (40lb) packet size..
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